Product Information Sheet (PDF)
• Chemically Defined
• Serum-Free and Xeno-Free
• No Plate Coating Necessary
• Performance similar to FBS Medium
Human mesenchymal stem cells (hMSCs) hold promise for the treatment of a wide variety of diseases. Currently, fetal bovine serum (FBS) is added to the medium to achieve expansion of hMSCs. However, concerns have been raised over animal-born pathogens, immune reactions and lot-to-lot variations caused by the undefined nature of FBS. To address these issues, StemRD has developed MesenGro®, a chemically-defined, serum-free and xeno-free medium for the expansion of hMSCs.
 |
Fig. 1: MesenGro® medium gives hMSCs a similar morphology as 10% FBS medium. No plate coating. |
 |
Fig. 2: MesenGro® medium allows a similar growth-rate of hMSCs as 10% FBS medium. Cell numbers per well (24-well plate) at each time point were counted with medium change every 2 days. |
 |
Fig. 3: MesenGro® generates a similar exponential expansion as 10% FBS medium for hMSCs. Total cell numbers per well (6-well plate) at each split (every 3 days) were counted. The starting passage number is 4 (from FBS), and starting cell density is 20,000/well. |
 |
Fig. 4: MesenGro® medium retains the multilineage differen-tiation potential of hMSCs after long-term culture. At passage 9, cells were plated in 6-well plate, and differentiation achieved in various media after 18-24 d. |
|
