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Antibody, Sonic Hedgehog (SHh)

Cat. #: MAB-SHH

Cat.# Description Size Quantity Price

MAB-SHH-050 mAb, human SHh 50 µg $475.00

MAB-SHH-250 mAb, human SHh 250 µg $1,775.00

MAB-SHH-1000 mAb, human SHh 1000 µg $5,775.00


Product Data Sheet (PDF)

The hedgehog pathway has drawn great attention recently as a novel therapeutic target for treating certain types of cancer. StemRD has generated a mouse monoclonal antibody against human and mouse SHh. This antibody has nM binding affinity to SHh protein, and importantly, is functionally blocking against human and mouse SHh. Data shown below is from an activity assay for inhibition of human SHh.

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 Fig. 2: A monoclonal antibody against SHh blocks the activity of human SHh. Activity is assessed by a Gli reporter gene assay in Swiss 3T3 cells against 20 ng/mL human SHh (from StemRD).

 



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