LDN-193189

$ 89.00

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  • LDN-002, 2 mg89.00
  • LDN-010, 10 mg219.00
  • LDN-050, 50 mg569.00
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Source M.W.406.48 CAS No.1062368-24-4
Structural InfoLDN-193189
FormulationPowder
ReconstitutionBefore reconstitution, we recommend a brief spin to drive down any material dislodged from the bottom of the tube. The compound is soluble in DMSO.
StabilityThe powder is stable for at least 2 year if stored at -20 °C. The dissolved compound is stable for at least 1 month at 4 °C, but should be stored in aliquots at -20 °C for longer term. Protect from light.
PurityGreater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity
Country of OriginUSA

A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2 and ALK-3).  Only weakly inhibits ALK-4,
-5, and -7.
4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline

Ref:  Cuny, G.D., et al. Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorg Med Chem Lett 18: 4388-92, 2008.