Thymosin-β4

$ 150.00

Select Size:

  • TB4-100, 100 µg150.00
-+
Add to Cart
Source M.W.4963.55 CAS No.
Structural InfoAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH
FormulationLyophilized in a solution of acetonitrile and TFA.
ReconstitutionBefore reconstitution, we recommend a brief spin to drive down any material dislodged from the bottom of the tube.  The lyophilized peptide should be reconstituted in sterile PBS.
StabilityThe lyophilized protein is stable for at least 1 year if stored at -80 °C. Reconstituted protein is stable for at least 1 month at 4 °C, but should be stored in aliquots at -80 °C for longer term. Avoid repeated freeze and thaw.
PurityGreater than 95% as determined by RP-HPLC analysis
Biological Activity
Country of OriginUSA

Thymosins are small polypeptides originally isolated from the thymus, but most are actually present in many other tissues. The archetypical β-Thymosin is Thymosin-β4, which is a cellular constituent in many tissues. In addition to its role as a major actin-sequestering molecule, Thymosin-β4 has a role in tissue repair. Such effect have been shown in animal models of tissue damage and now in human clinical trials. Recently, Thymosin-β4 was shown to stimulate regeneration of adult cardiac progenitor cells in a paper published in Nature (Smart, et al., Nature, 2011, June 8th).  

Amino Acid Sequence:
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH